

When spring is in the air in Japan and iron storm by Russia were starting to cover Ukraine, the author has released several articles on this web site, basing on population genetics papers which clearly indicate the ineffable unusual genetlc structure of Korean gene. It is at the heart of genetic research for an isolated and homogeneous ethnic population that analyzing of inherent variants and the frequency of the gene provides more information for promoting mental and physical health of the population. To my regret, figuratively speaking, I strongly feel that The Koreans need "gene therapy", but it is needless to say that it's impossible to do comprehensive "gene therapy" for humans except for rare genetic disease even in the revelation of modern genetic technology.
Korean actress. There are no Korean women who won international beauty pageants in the past ten years.

We, humans around the world, should know the fact that The Koreans carry strange genetic architecture.

Please strongly keep in your minds that the following quotations from population genetics paper clearly indicate peculiarity of The Koreans gene.
[Citation from population genetics paper#1]
Based on our analysis, we hypothesize that Koreans might have different responses to the above mentioned terms-related drugs, when compared to other populations.
Therefore, we rationally conjectured that Korean only SNVs prevalent across many of the individuals would be more important for treating Koreans differently from other populations in the personalized medicine.
Therefore, we inferred that special attention should be made for the Korean population when treated for the above mentioned terms related diseases, since other populations did not carry those Korean only SNVs.
United States Department of State do make a warning to young women's journeys to South Korea about sexual assault. Please strongly note that the United States don't make same warning to other countries (i.e. China, Japan etc.)

Sexual Assault: The Embassy regularly receives reports of sexual assault from U.S. citizens. Most cases involved young women assaulted by acquaintances they met on social media, dating, or messaging apps. Alcohol is often involved, and Korea’s low overall crime can create a false sense of security. Specialized hospital units and police are available in South Korea to assist victims, however services in English and responsiveness to the crime are not always consistent. In general, sex crimes are not punished as harshly in South Korea as in the United States and the road to prosecution is a challenging one for victims.

Women’s safety
Women travelling alone may be subject to certain forms of harassment. Sexual assault and harassment do occur, particularly around bars and nightlife areas, such as Itaewon and Hongdae-Ipgu.
Local authorities may not always respond adequately to reports of sexual violence and harassment. If you are sexually assaulted, you should report it immediately to local authorities and to the nearest Canadian government office.
- Avoid travelling alone, especially at night
- Remain vigilant
- Be careful when dealing with strangers or recent acquaintances
What is "family-destroying criminals"?
The Korean "Comfort Women": Movement for RedressChunghee Sarah Soh
Dec 1996
In resent years, young male criminals in South Korea take advantage of this traditional view by raping women in front of members of their families in order to ensure that robbery would not be reported to police. The media refers to these raping robbers as "family destroying criminals" because of the shattering impact of their behavior on the viability of the family; the raped woman is now sullied in the eye of her husband, herself, and other members of the family, which may eventually break up under the psychological strain.
Stupid lie and scam.
Koreans who lies all the time like breathing because of unusual genetic structure of DNA
Historical facts

Looking N.W. along a street in the native (old) Pusan, Korea 1904 year

White-robed pottery peddlers on the streets of Seoul, Korea 1906 year

Little Korean girls, of the middle class, in the northern suburbs of Seoul, Korea 1904 year
Could you understand ?
Please gaze red circle, and please remember that it's 1904=20th century !

1886 year? photographer name:Hayashi, Northwest entrance gate to Seoul, Korea
It nauseously are the most absurd lie and scam


Strange phenomenon in South Korea
Total fertility rate in South Korea is abnormal !
Although it's a conundrum that why South Korea women don't want to have children, there could be no dispute that only competition in university entrance exam is fair competition in South Korea. Therefore, they must spend huge money for enrolling into prestigious university, and pupils in high school are forced to learn for long hours every day, so high expenses to university entrance exams may be the reason for extreme low fertility rate in South Korea. In other word, the source of low birth rate is competitive personality among The Koreans.
Please strongly keep in minds South Korea indicates tremendously low figure in total fertility rate, South Korea continue in "War-Time" but not "Peace-Time".
Korean Actress. Please notice that Korean women have "same jawline" below as the result of cosmetic surgery.

Suicide rates is the highest in the world

A great majority of researchers in South Korea make a pretext of that old Koreans indicates high suicide rate compared with adolescents as for why suicide rate in South Korea is the highest in the world.
However, in part due to deliberately focus on suicide rate, i think that the essence that Koreans carry inherent variants of MDD(major depressive disease) deliberately have been overlooked.
It is a complete and scientific fact and is beyond all doubts that the Koreans carry numerous brain-related variants inherent to the Koreans which might be the cause of The Koreans specific mental disorder i.e. "Hwabyung" , and please understand that it is never racism and sneers to Koreans.
The exact investigation by OECD clearly indicates the fact of The Koreans intellectual ability
A great majority of Koreans have a daydream that "we are an excellent ethnic group", therefore, Koreans explicitly show contemptuous attitudes that "stupid people like Southeast Asia's people should be obedient to excellent people like Koreans". As the natural result, Southeast Asia's people who frequently and dairy contact with Koreans hate Koreans except for K-POP fans who aren't in daily contact.However, there is the following clear data in "Survey of Adult Skills (PIAAC)" by OECD (The Organization for Economic Co-operation and Development ) !

Please awake and stand up Thailanders, Vietnamese and Filipino to The Koreans gene !
abnormal obsession to cosmetic surgery
I don't know cosmetic surgery expenditure of K-POP stars, but it is beyond all doubts that all K-POP stars did plastic surgery.Please confirm that "all women are same jawline".

Gender, Globalizationand Aesthetic Surgeryin South Korea
Ruth Holliday(proffessor in University of Leed and Joanna Elfving-Hwang Curtin University
May 2012
This article explores the unusually high levels of cosmetic surgery in South Korea – for both women and men. South Korean’ alleged ‘obsession’ with cosmetic surgery regularly hits headlines both in Asia and the ‘West’ because of its reportedly high take-up rate by both women and men. Cosmetic surgery and skin treatment clinics are now commonplacein urban shopping malls, viewed much like nail and beauty salons in the UK, and providing procedures such as laser removal ofblemishes to 'walk-in’ customers.
virtually, no winners of famous scientific prizes
As the results of my investigation about internationally famous science-related awards including Novel prizes, I found that Koreans winners are exceptional cases in spite of large population size.result in 2024 | South Korea | Japan | Taiwan |
prizes winner | 1 | at least over 211 | 13 |
population size (ratio:South Korea=1.0) |
1.0 | 2.5 | 0.5 |
I conducted two investigations, first in 2018 and second in 2024, and there is no award winners in the first investigation, afterward i found that only one award winners in the second investigation as the above, the first result is as follows.
result in 2018 | South Korea | Japan | Taiwan |
prizes winner | 1 | at least over 195 | 11 |
From population genetics paper
According to several population genetics papers, it is beyond all doubts that the genetic structure of Koreans is astonishingly unique and strange.Koreans have high percentages of non-synonymous variants compared with other ethnic population (the Japanese, the Chinese etc)
A subset of the nsSNPs showed remarkably high allele frequencies among the Koreans studied compared to other populations, including Europeans and west Africans represented in the HapMap project.
In contrast with the SNVs common to other populations in HapMap and 1KGP, the Korean only SNVs had high percentages of non-silent variants, emphasizing the unique roles of these Korean only SNVs in the Korean population.
The portion of non-synonymous SNVs in the ‘1000GP rare’ class was more than twice what was observed in the other classes.
It is possible that these patterns are associated with purifying selection to rapidly remove deleterious alleles in the population

As opposed to the other ethnic population, variants which are inherent to Koreans extremely biased to the parts of Koreans.
Figure 2b shows that nearly 60.59 % (735,271) of Korean only SNVs are observed in only one individual, while 1.04% (12,640) of Korean only SNVs are observed in all 35 individuals. Therefore, we rationally conjectured that Korean only SNVs prevalent across many of the individuals would be more important for treating Koreans differently from other populations in the personalized medicine.

Cited from population genetics paper #3

MAF(minor allele frequency) clearly differs from the other ethnic population, including the Japanese, the Chinese.
The variants distribution of Koreans completely differs from The Japanese in spite of same East Asians, and needless to say, differs from other populations too, please see below cited contents.12859_2014_6653_MOESM5_ESM.jpg from population genetics paper #1

The overwhelming majority of variants which are inherent to Koreans have in relation to mental diseases, personality disorders and human mentality.
List of genes in which there are genetic mutations(=variants) peculiar to Koreans extracted from paper #1 and search results by gene name at NCBI(National Center for Biotechnology Information in USA) is as follows.
SNV-1 means number of Koreans peculiar variants in paper #1



Please note that the above genetic facts that Korean peculiar variants are clearly related to human brain coincides with the fact that almost no one Koreans have a few winners of internationally renowned science-related awards, including the Nobel Prize.
Secondly, please know the fact that the vast majority of Koreans peculiar variants(=mutation) are mental disease susceptibility genes, according to my investigation.

Name: Kazuo Ueda (researcher of Korean history)
Country: Japan



population genetics paper #1 (FDA)
Whole genome sequencing of 35 individuals provides insights into the genetic structure of Korean population
Wenqian Zhang et al.
Published: 21 October 2014
The following content is the "meta tag" for the website where the above paper is posted, in other word, the above paper was written by Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, USA
In contrast with the SNVs common to other populations in HapMap and 1KGP, the Korean only SNVs had high percentages of non-silent variants, emphasizing the unique roles of these Korean only SNVs in the Korean population.
Specifically, we identified 8,361 non-synonymous Korean only SNVs, of which 58 SNVs existed in all 35 Korean individuals.
Based on our analysis, we hypothesize that Koreans might have different responses to the above mentioned terms-related drugs, when compared to other populations.
Therefore, we rationally conjectured that Korean only SNVs prevalent across many of the individuals would be more important for treating Koreans differently from other populations in the personalized medicine.
Therefore, we inferred that special attention should be made for the Korean population when treated for the above mentioned terms related diseases, since other populations did not carry those Korean only SNVs.
According to the SNV compositions (Figure 3), we found that the most prevalent changes in all three SNV sets was C:G->T:A transition, the same trend as the raw base substitution mutational spectrum in humans [42]. In addition, we found that Korean SNVs and SNV-1 occurred more frequently at C/G base pairs, which was consistent with previous findings [42]. Nevertheless, almost half of SNV-35 mutations occurred at T/A base pairs.

population genetics paper #2
Extensive genomic and transcriptional diversity identifiedthrough massively parallel DNA and RNA sequencing of eighteen Korean individuals
Young Seok Ju et.al
2011
A subset of the nsSNPs showed remarkably high allele frequencies among the Koreans studied compared to other populations, including Europeans and west Africans represented in the HapMap project.
We found a subset of genes to be highly enriched for nsSNPs, here called super nsSNP genes
population genetics paper #3
Analysis of protein-coding genetic variation in 60,706 humansMonkol Lek et.al
Nature 17 August 2016
Deleterious variants are expected to have lower allele frequencies than neutral ones, due to negative selection. This theoretical property has been demonstrated previously in human population sequencing data12,13 and here (Fig. 1d, e).
population genetics paper #4
Korean National Standard Reference Variome database of whole genomes with comprehensive SNV, indel, CNV, and SV analyses
Nature Published: 04 April 2018
Jungeun Kim et.al
Surprisingly, however, roughly half of the variants in ‘1000GP low frequency’ were classified as ‘frequent in KoVariome’.
Despite their close geographic proximity, the Korean population was shown to be genetically distinct from the Chinese and Japanese populations, highlighting the need for a Korean-specific variome to accurately identify rare disease variants in this population.
population genetics paper #5
Korean Genome Project: 1094 Korean personal genomes with clinical information
Science Advances 27 May 2020
Sungwon Jeon et.al

While singletons reflect the difference in the number of samples between The Koreans and The Japanese, the lack of difference in the number of "common" variants indicates the clear difference in variants distribution between the two, which is fully consistent with results from other population genetics papers.
In other word, there are remarkably different of gene frequency between The Koreans and Others (The Japanese, etc.) at frequencies between 1% and 5%.
Please gaze with great attention the first figure in this article with the above figure, you will be able to understand the scientific fact of genetic architecture peculiar to The Koreans.
Believe it or not, that is the fact.
South Korea has recorded the world's lowest birth rate and the world's highest suicide rate, and North Korea (=Kim dynasty) is the largest absolute monarchy in the world. Figuratively speaking, South Korea might be "huge mental hospital", and North Korea may be "huge POW camp".
